Please enable JavaScript.
Coggle requires JavaScript to display documents.
Marginal Keratitis:an inflammatory disease of the peripheral cornea,…
Marginal Keratitis:an inflammatory disease of the peripheral cornea, characterized by peripheral stromal infiltrates which are often associated with epithelium break down and ulceration. It is usually associated with the presence of blepharoconjunctivitis, and is thought to represent an inflammatory response against S. aureus antigens.
-
Pathophysiology
The presence of bacterial antigens in the peripheral area of the cornea possibly triggers a type III hypersensitivity reaction, in which immunocomplexes are formed and deposited in the peripheral corneal stroma. here are subsequent complement pathway activation and neutrophil attraction, with the formation of a peripheral stromal opacity also called catarrhal infiltrate. This lesion may evolve with epithelial damage, forming a marginal ulcer
Risk factors
-
longstanding blepharitis, conjunctivitis, or meibomitis
-
-
Symptoms
-
-
-
-
-
Eyelash changes like madarosis, poliosis, trichiasis, and the presence of hard scales in the base of eyelashes
-
-
-
Treatment
Treatment of blepharitis
-
short course of oral abx doxycycline, tetracyclin, azithromycin
-
-
-
-
-