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Neuron to Glia - Coggle Diagram

- - - - origin
      - activation
      - interaction with neuron
        
        delicate microglial processes contact synapse
        
        express NTM receptor
        
        soluble factors implicated in neuron-microglia interactions
        
        participate in synaptic pruning
        
        glutamate sensing, lysome
        
        microglia-derived BDNF supports spine plasticity/learning
        
        release ATP
    - - characteristics
        
        melination to 50+ cells in CNS
      - interactions with neuron
        
        energy supply (new hypothesis
        
        saltatory AP conduction
    - - characteristics
        
        NG2 cell
      - sense neuron
        
        express voltage-gated K+ & Na+ channel
        
        express Glu receptor
        
        neuron-OPC cell synaptic communication
        
        OPC respond to schaffer collateral stimulation
        
        glumatergic input
      - affect neuron
        
        promotes differentiation
        
        myelination plasticity?
    - - characteristics
        
        electrically passive cells
      - sense neuron
        
        ensheath synapse by processes
        
        maintain sodium and potassium homeostasis,
        
        NTM uptake and metabolism
        
        Ca2+ signaling
      - affect neuron
        
        gap junction
        
        synaptogenesis
        
        synaptic pruning