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Peripheral giant cell granuloma, Etiology, Epidemiology, CCD-3-118-g006,…
Peripheral giant cell granuloma
nodules of multinucleated giant cells derived from osteoclasts.
Fibrillar and reticular connective tissue stroma
extravasated red blood cells
ovoid and spindle-shaped mesenchymal cells
Clinical examination
Intraoral
Gingiva
Deep red to blue
Swelling
Smooth or ulcerated
No bleeding
Firm consistency
Alveolar ridge
Asymptomatic bluish-purple nodule
Irritation fibroma
Sessile or pedunculate
Size < 2 cm
Alveolar bone resorption
Extraoral
Facial swelling without palpable lymph nodes
Radiographic examination
Periapical radiographic
Alveolar bone
Cup shaped radiolucency
Superficial erosion
Histologic examination
Biopsy
Multinucleated giant cells in CNT
Spindle shaped. Mesenchymal cells
Dystrophic calcification
Hemosiderin
PNMs
unknown
local irritation
has been suggested to
contribute to the development of the lesion
local irritaion due to
periodontal disease
poor dental restorations
calculus
ill-fitting dental appliances
dental plaque
dental extractions
Prevalence
PGCG is
uncommon but not rare
.
Its incidence and prevalence
in the general population
have not been definitively determined.
Race
:
No racial predilection
is associated with the disease
Sex
:
no sex predilection
(52% in female and 48% in male)
Age
:
fifth to seventh decades
of life at the time of diagnosis of this lesion.
Firm, soft, Bright nodule
Sessile or Pedunculated mass
Occasionally ulcerated surface
Vary in size
Estrogen
Periodontal disease
Xerostomia
Improper restoration
Poor oral hygiene
Excisional biopsy (ตัดรอยโรคออก)
รายงานพบ มีโอกาสเกิดรอบโรคซ้ำ 10% หลังการรักษา
ทำความสะอาดฟันซี่ข้างรอยโรค (Plaque & Calculus)
Amelanotic melanoma
Central giant cell granuloma
Pyogenic granuloma
Lymphagioma
Peripheral ossifying fibroma
Hemagioma
Fibrous hyperplasia
Metastatic tumors
Inflamed iritation fibroma
Etiology
Epidemiology
Examination
Histology
Predisposing factor
Differential Diagnosis
Clinical Appearance
Management
