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Antiphospholipid Syndrome - Coggle Diagram
Antiphospholipid Syndrome
What is APS?
elevated levels of proteins to fight off foreign substances: associated with clots in the veins and arteries
Two classes of antiphospholipid (aPL) antibodies: anticardiolipin antibodies and lupus anticoagulant
Two main classifications for APS: if there is no underlying autoimmune disorder the person has primary APS, if the individual has SLE or another underlying autoimmune disorder, the person is said to have secondary APS.
Even though they are broken into two categories research suggests there is little difference between the two
Signs, Complications, and Conditions
first shows up as a blood clot in an artery or vein, or a blockage of a blood vessel caused by a clot moving, or recurrent pregnancy loss
low platelet count
certain skin problems
neurological signs
heart valve disease
certain autoimmune diseases
high blood pressure
sensorineural hearing loss
Conditions associated with APS
Systematic Vascular Thrombosis:
Pregnancy loss and other complications
Thrombocytopeniz
skin disorders
stroke and other neurological disorders
heart valve disease
lupus and other autoimmune disorders
Diagnosis
based on clinical and laboratory findings: after an individual experiences many of the signs, symptoms
two main tests for antiphospholipid antibody tests: to diagnose APS it is standard practice to use both tests and repeated 6-8 weeks later to confirm the presence of aPL antibodies
Who gets APS?
no clear pattern of inheritance, no gene identified
Treatment
individualized based on person's current health status