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Autosomal dominant polycystic kidney disease - Coggle Diagram
Autosomal dominant polycystic kidney disease
What is it?
common form of polycystic kidney disease
present at birth in all races
cyst growth on both kidneys: which leads to kidney failure and reduced function
can also causes cysts on other organs such as the heart and blood vessels in the brain
Symptoms
adult onset
live for decades without any problems
high blood pressure is a common result of ADPKD
Diagnosis
ultrasound
CT scan
MRI
Two genes associated with ADKPD
Genetic tests can detect mutations in the genes:
cannot
predict onset or severity of disease
prenatal testing is available
Treatment
aimed at treating kidney and non-kidney symptoms
blood pressure is followed and treated with medications if needed
pain with kidney is managed by pain medications and antidepressants or removing painful cystic fluid from kidney
kidney treatment is based on individual needs
Inheritance
ADPKD is inherited as a autosomal dominant trait in families
one parent has the disease and 50% chance the child will have the disease
new mutations make up 1/5 of new cases