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The Nervous System, image - Coggle Diagram
The Nervous System
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Neurotransmitter
Dopamine
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1) Stimulus above threshold
2) Ca2+ channels open
Ca2+ ions enter
3) Exocytosis of dopamine
dopamine binds to receptors
of postsynaptic membrane
(for short time)
4) Na+ channels open
Na+ ions enter
(depolarization/EPSP)
5) Happiness and pleasure
(for short time)
6) Presynapse recycle (re-uptake)
the excess dopamine
(remains in cleft for few seconds)
Parkinson's disease affects the nerve cells in the brain that produce dopamine. Symptoms: muscle rigidity, tremors, and changes in speech. After diagnosis, treatments can help relieve symptoms, but there is no cure.
Acetylcholine
in motor neurons, parasympathetic NS, and brain
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Myasthenia gravis (MG) is a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness. The most commonly affected muscles are those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. (Parent disease: Neuromuscular disease
Parent cause of death: Autoimmune disease)
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Congenital Myasthenia gravis is not an autoimmune disease. It is a genetic defect leading to an abnormal acetylcholine receptor.
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