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renal pharmacology - Coggle Diagram
renal pharmacology
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mannitol
for drug overdose, elevated ICP,IOP
contraindicated in anuria, HF
osmotic diuretics; ↑tubular fluid osmolarity→↑urine flow, ↓intracranial/ocular pressure
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aliskiren
direct renin inhibitor, block conversion of angiotensinogen to angiotensin1
contraindicated with ACE inhibitors or ARBS, in pregnancy
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acetazolamide
for glaucoma, metabolic alkalosis, altitude sickness, pseudotumor cerebri
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loop diuretics
furosemide, bumetanide, torsemide
for edema, hypertension, hypercalcemia
adverse: ototoxicity, hypokalemia, hypomagnesemia, dehydration, allergy, metabolic alkalosis, nephritis, gout
sulfonamide loop diuretics; inhibit cotransport(Na/K/2Cl) of thck ascending loop; stimulate PGE release
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thiazide diuretics
for HTN, HF, idiopathic hypercalcemia, nephrogenic DI, osteoporosis
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