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Sickle cell anaemia - Coggle Diagram
Sickle cell anaemia
Symptoms
Fatigue
Dizziness
Pain
in joints
in chest
Malaise
Infection
Blood in urine
Abnormal breakdown of red blood cells
Complications
acute chest syndrome
Pulmonary hypertension
Stroke
Organ damage
Blindness
priapism
Treatment
for children and teenagers
Stem cell transplant
Devices
Patient controlled analgesia
Depends on severity
Bone marrow transplant
Blood transfusion
Medication
Vitamin and blood transfusion
Chemotherapy
Norcotic
autosomal recessive disorder result from structural abnormalities of haemoglobin
Common among African descent
Inheritance
Both mother and father must pass the defective from of the gene for a child be affected
The sickling is promoted by conditions associated with low oxygen levels, increased acidity or low volume if bood
Caused by mutation in the gene