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MPL - Coggle Diagram
MPL
Haematopoietic diseases
Anemia
You don't have enough healthy red blood cells to carry adequate oxygen to your body's tissues.
Thymoma
Tumor originating from the epithelial cells of the thymus that may be benign or malignant
Leukemia
Cancer of the blood or bone marrow
Myeloma
Damage the bones, immune system, kidneys, and red blood cell count.
Splenomegaly
Condition that Happens when your spleen becomes enlarged
Mycosis fungoides
T-cell lymphoma
Affects the skin
Thrombopoietin receptor protein
Proliferation of certain blood cells called megakaryocytes
Produce platelets, the cells involved in blood clotting
Growth and division of cells
Blood conditions
Thrombocythemia
Bone marrow makes too many platelets
Having too many platelets makes it hard for your blood to clot normally.
Myelofibrosis
Bone marrow cancer
Disrupts your body's normal production of blood cells
Extensive scarring in your bone marrow
Severe anemia that can cause weakness and fatigue
Two research studies that took place.
Systematization of analytical studies of polycythemia vera, essential thrombocythemia and primary myelofibrosis, and a meta-analysis of the frequency of JAK2, CALR and MPL mutations: 2000–2018
Molecular Research; New Molecular Research Study Findings Recently Were Reported by H.J Freisleben and Co-Researchers [The Main (Glyco) Phospholipid (MPL) of Thermoplasma acidophilum]
Proto-oncogene or Tumor suppressor
Proto-oncogene