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Ulcerative Colitis - Coggle Diagram
Ulcerative Colitis
Risk Factors
Resident of United States/Western Country
Age 30-39
Causes
Unknown causative agent
Lesions in crypts of Lieberkuhn
Formation of pinpoint mucosal hemorrhages
Lesions become necrotic/ulcerative
Combination of factors
Intestinal microorganisms
Intestinal epithelial dysfunction
Aberrant immune response
Collaborative Treatments
Mild-Moderate
Avoid Certain Food Products
Caffeine
Lactose
Highly spiced food
Gas-forming food
Fiber supplement
Severe
Same as Mild-Severe
Surgical Treatment (if not responsive to other methods)
Ileostomy
Ileoanal anastomosis
Pharmocological
5-ASA Compounds
Corticosteroids
Immunomodulating drugs
anti-TNF Therapy (for Severe)
Probiotic therapy
Labs/Diagnostics
Sigmoidoscopy
Colonoscopy
Should not be performed on persons with SEVERE disease (risk for perforation)
Biopsy
Stool Exam
Clinical Manifestations
Systemic
Axial Arthritis (Spine, sacroiliac joint)
oligoarticular arthritis (large joints of arms/legs)
Inflammation of the eye
Skin lesions
Blood disorders
Anemia
Hypercoagulability
Mucous membrane inflammation
Bile duct inflammation
Other
Persistent Diarrhea
Bloody stool
Mucus passed with bowel movement
Mild abdominal cramping
Fecal incontinence
Anorexia
Weakness
Fatigability
Mild
Less than four formed or liquid stools daily
Intermittent Rectal bleeding
Urgency
LLQ Cramping
Most Common
Moderate
More severe diarrhea
More severe bleeding
Abdominal pain
Tenderness
Fever
Anemia
Severe
More than 6 bloody bowel movements a day
Severe anemia
Hypovolemia
Impaired nutrition
Hypoalbuminemia
Complications
Colon Cancer
Severe Anemia
Prominent Hypovolemia
Impaired nutrition
Crypt abscesses
pseudopolyps
Acute
Intestinal Obstruction