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Crohn's Disease - Coggle Diagram
Crohn's Disease
Clinical Manifestations
Systemic
Bile duct inflammation
Mucous membrane inflammation
Eye inflammation
Blood Disorders
Anemia
Hypercoagulability
Oligoarticular arthritis (large joints of arms/legs)
Skin lesions
Axial Arthritis (Spine, sacroiliac joint)
Other/Principal Symptoms
Intermittent diarrhea
Less bloody than UC
Colicky pain (LRQ)
Weight loss
Fluid/Electrolyte disorder
Malaise
Low-grade fever
Ulceration of perianal skin
Nutritional deficiency (related to segment of intestine)
Childhood
Growth & Development retardation
Causes
Unknown Causative Agent
Sharply demarcated, granulomatous lesions
Collaborative Treatment
Goals
Terminate inflammatory response
Promote Healing
Maintain adequate nutrition
Prevent/Treat Complications
Nutritious Diet (ie Elemental)
HIGH in:
Calories
Vitamins
Protein
Free of:
Residue
Bulk
Fats
TPN
If food unable to be absorbed from intestine
Pharmocological
5-ASA agents
Corticosteroids
Antibiotics
Immunosuppressant drugs
Anti-tumor necrosis factor (TNF) therapy
Surgery
Resection of damaged bowel
Abscess drainage
Fistula repair
Complications
Fistula formation
ileum= common site
May lead to
malabsorption
bacterial overgrowth
diarrhea
Abdominal abscess
Intestinal obstruction
Risk Factors
Female
Age 20-39
Labs/Diagnostics
Endoscopy
Direct visualization of affected area
Determine extent
Biopsy
Exclude Infection Agent
Stool Culture
Examination of fresh stool
CT Scan
Radiographic contrast