Please enable JavaScript.
Coggle requires JavaScript to display documents.
Mesothelioma - Coggle Diagram
Mesothelioma
Clinical Presentation
-
-
-
-
-
Signs of metastases; lymphadenopathy, hepatomegaly, bone pain/tenderness, abdominal pain/obstruction
-
Treatment
-
-
Generally it is resistant to surgery, chemotherapy and radiotherapy
-
-
-
Pathophysiology
Tumour begins as nodules in the pleura which extend as a confluent sheet to surround the lung and extend into fissures
The chest wall is often invaded, with infiltration of intercostal nerves, giving severe intractable pain
It is a high grade malignancy of the pleura, that spreads around the pleura surfaces, but can also start in the pericardial space, peritoneal space and in the paratesticular space
Lymphatics may be invaded, giving hilarity node metstases
Key Facts
-
Other sites include the mesothelial cells of the peritoneum, pericardium and testes
-
Diagnosis
-
-
CXR & CT
- Unilateral pleural effusion
- Pleural thickening