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An elderly female patient has a history of osteoporosis, chronic type II…
An elderly female patient has a history of osteoporosis, chronic type II diabetes mellitus, and high blood pressure. She has come to the doctor today because she has noticed blood in her urine. Her doctor is now primarily concerned about the effect of high blood pressure on her kidneys and. the effect of low kidney function on her already compromised bone mass. What could be going on that explains all of this? How are blood pressure, kidney function, and bone mass related?
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Downstream
people with diabetes also develop high blood pressure, which can also damage your kidneys.
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Background
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Nephron
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Structure
Renal Corpuscle
Glomerulus
tangle of capillary loops, glomerular capillaries
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Renal Tubule
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Nephron loop
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lining changes from simple cuboidal epithelium (thick segment) to simple squamous (thin segment) then back to simple cuboidal
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How urine is formed
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Reabsorption
return of components from within tubular fluid to blood within peritubular capillaries and vasa recta
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