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Hyperadrenorticism in dogs, NAME: NURDIANA BINTI AB HALIM MATRIC NO.:…

- - - - Collect urine sample when the pet is not stressed
      - urine cortisol excretion increases in compared to creatinine in dogs with hyperadrenocorticism
    - - collect a blood sample before and after administration of dexamethasone, 0.01-0.015 mg/kg IV or IM
      - With PDH, no or partial suppression of ACTH since feedback does not work normally
      - With FAT, the tumor secretes mainly of ACTH influence so ACTH suppression has little to no effect on cortisol concentration
  - - - Adrenal tumors are visible on routine abdominal radiograph in approximately 50% of cases of adrenal-dependent hyperadrenocorticism.
      - Mineralization of adrenal tumors occurs in about 50% of both adenomas and adenocarcinomas.
      - Hepatomegaly is present
- - - - Destroys glucocorticoid-secreting cells of the adrenal cortex
      - Administration recommended twice daily for induction at 40-50mg/kg
      - For maintenance, 50 mg/kg/week divided into 2 to 3 doses over the course of a week
  - - - Optimal treatment in some dogs with unilateral adrenal tumors.
      - Considerable effort should be made to ensure that gross metasatasis or invasion of surrounding structures such as the caudal vena cava has not occurred prior to surgery