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Cardiovascular Drugs - Coggle Diagram

- - - - ACE inhibitors
        
        Benazapril
        
        Enalapril
      - Angiotensin REceptor blockers
        
        Telmisartan
      - Sildenafil
      - Nitroprusside
    - - Calcium Channel blockers
        
        hydralazine
        
        Amlodipine
  - - - hydrochlorothiazide
      - spironolactone
      - Furosemide
    - - Nitroglycerin
      - Isosorbide
  - - - Atenolol
      - Propranolol
    - - Diltiazem
  - - - Beta -agonists/sympathomimetics
        
        Dopamine
        
        Dobutamine
    - - pimobenden
    - - Digoxin
- - - - Potassium Channel Blockers
        
        Amiodarone
        
        primary use for life threatening ventricular tachyarrhythmias
        
        Sotalol
        
        nonselective B blocker that also blocks myocardial K channels
        
        possible value in ventricular tachyarrhythmias
        
        negative inotrope and pro arrhythmic effects possible
        
        Prolong the action potential and refractory period
    - - calcium channel blockers
        
        diltiazem
        
        minimal effects on VSM
        
        Dogs with Afib
        
        Blocks myocyte calcium channels
        
        Slowing of SA/AV node
        
        good for supra ventricular tachyarrhythmias (aFib)
    - - Beta-blockers
        
        propanolol
        
        Esmolol
        
        atenolol
        
        inhibition of sympathetics
        
        For supra and ventricular tachyarrhythmias
    - - digoxin
        
        Supraventricular tachyarrhythmias (Afib)
        
        increases parasympathetic nerve activity at SA node, atria, and AV node
        
        Caution with hypokalemia or hypercalcemia
    - - 1A
        
        Sodium channel blockers
        
        Procainamide
        
        quinidine
        
        used for Afib in horse
        
        pro arrhythmic
      - 1B
        
        SodiumChannel Blockers
        
        Mexiletine
        
        Lidocaine
        
        ventricular arrhythmias only
        
        technically only licensed as anesthetic
        
        toxicity=seizures, ataxia, more in cats
      - slows conduction velocity in myocardium
  - - - glycopyrrolate
      - Atropine
      - most useful in sinus Bradyarrhythmia and 2nd degree heart block, conditions with high vagal tone
    - - Terbutaline
      - Isoproterenol
      - these increase Sinus node rate and AV conduction