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LIVER FLUKE DISEASE, WhatsApp Image 2020-07-15 at 3.10.58 PM - Coggle…
LIVER FLUKE DISEASE
Clinical signs
Bottle jaw
weight loss
aneroxia
Marked decrease in production
pale gum and membrane around eyes
GENERAL INTRODUCTION
Fascioliasis is a parasitic infection known as fluke
Fasciola hepatica
Common liver fluke or sheep liver fluke
Fasciola gigantica
May infecting human
causes liver condemnation
Reduction in milk and meat yield
Lymnaea as intermediate host in the water plant
cattle, sheep, goat and human as definitive host
CONTROL & PREVENTION
No vaccine to protect against Fasciola infection
Avoid animal grazing watercress or other water plants
Fecal egg count to monitor efficacy of Triclabendazole
Good management of livestock
TREATMENT
Triclabendazole
Nitroxynil
Clorsulon
CAUSES AND PATHOGENESIS
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PATHOGENESIS OF CHRONIC LIVER FLUKE
Moderate number of metacercaria ingested over a longer period of time
Immature larvae penetrate the lumen
Penetrate into peritoneal cavity
Tunnel through liver capsule
Migrate to bile duct
Chronic: Mature to adult and laying eggs
Feeds on bile duct wall cause hemorrhage and blood loss
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Irritates bile duct mucosa
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eggs production start 8-10 weeks after infection
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necrosis
Liver parenchyma is extensively fibrosed due to post-necrotic healing and scarring
CAUSES
Grazing animals are infested through ingestion of infected grass
Ingestion of fresh water plants with metacercaria or drinking water with floating metacercaria
Causal agent: Fasciola gigantica, Fasciola hepatica etc
Diagnosis
sedimentation
Flukefinder
