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Altered Hormonal and Metabolic Regulation - Coggle Diagram
Altered Hormonal and Metabolic Regulation
impairment of the hypothalamic-pituitary axis
too little excretion of hormone
too much excretion of hormone
Diabetes Insipidus
manifestations
polyuria
excessive thirst
dehydration
treatment
hydration
pharmocologic: desmopressin
correction of the cause
diagnosis
dehydration, enlarged bladder
low serum solute concentration, ADH levels, specific gravity of urine
Hyperthyroidism
treatment
gland destruction
pharmacologic block of thyroid hormone
manifestations
enlarged thyroid gland
excessive metabolic rate
weight loss, sweating, tachycardia, palpitations
diagnosis
enlarged thyroid gland
serum TSH measurement: thyroxine needed
T3 and T4 levels
Addison Disease
treatment
IV fluid replacement along with hydrocortisone
salt increase, lifelong glucocorticoid replacement
diagnosis
electrolyte levels demonstrating hyponatremia and hyperkalemia
serum corticosteroid levels
manifestations
hyper pigmentation, hypotension, shock
impairment of the endocrine gland
inactive hormone
Hypothyroidism
manifestations
fatigue, cold intolerance, weakness, weight gain, dry skin, coarse hair, lethargy, impaired reproduction
treatment
replacing hormone: pharmacologic
diagnosis
TSH, free t4, total t4, t3 uptake, thyroid antibodies
Cushing Syndrome
diagnosis
24 hour urine collection; noting elevated cortisol
treatment
removing cause of excess hormone production
manifestations
metabolic alterations, obesity, osteoporosis, behavioral changes
impairment of receptor binding
receptor binding inadequate
target cell unresponsive
impairment of feedback mechanisms
impaired feedback loop
ectopically produced hormone
SIADH
manifestations
decreased urine output
concentrated urine output
associated with hyponatremia: nausea, vomiting, headache, muscle cramps, weakness
diagnosis
hyponatremia, hypotonicity, decreased urine volume, concetrated urine, absence of renal/adrenal/thyroid abnormalities
treatment
water restriction
IV hypertonic saline
pharmacologic
impaired metabolism or elimination
impaired inactivation
impaired elimination