Please enable JavaScript.
Coggle requires JavaScript to display documents.
Systemic Vasculitis - Coggle Diagram
Systemic Vasculitis
-
Key Facts
-
-
Can be seen in many diseases including RA, SLE, polymyositis and some allergic drug reactions
Conditions which are associated include: subacute infective endocarditis, vasculitis with RA, SLE, scleroderma, polymyositis/dermatomyositis, Goodpasture syndrome and inflammatory bowel disease
Inflammation and necrosis of blood vessel walls with subsequent impaired blood flow resulting in:
- Vessel wall destruction (aneurysm, rupture and stenosis) - resulting in perforation and haemorrhage into tissue
- Endothelial injury - resulting in thrombus + ischaemia/infarction of dependent tissues
-
Classification
-
-
By size of blood vessel involved and presence or absence of anti-neutrophil cytoplasmic antibodies (ANCA)