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DIURETIC (Furosemide) (Side effects (Nausea and vomiting, Dizziness,…
DIURETIC
(Furosemide)
Side effects
Nausea and vomiting
Dizziness
Diarrhea
Headache
Stomach cramps
Muscle pain
Itching or rash
Restlessness
Blurred vision
Mechanism of action
In the thick ascending limb of loop of Henle
By binding to the chlorode transport channel
Inhibit the luminal Na-K-Cl contrasporter
Thus causing Na-K-Cl loss in the urine
Contra indication
Renal failure or renal impairment
Hypovolema
Anuria
Hypotension
Hypersensitivity to furosemide
Storage
Store below 25°C
Route of administration
Oral or intravenous 40mg over 1-2 minutes
Indication
High blood pressure
CHF
Fluid retention (oedema)