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ANTIBIOTICS (Vancomycin) (Side effects (Irregular heartbeat, Loss of…
ANTIBIOTICS
(Vancomycin)
Contra indication
Low level of white blood cell
Hearing loss
Kidney disease with likely reduction in kidney function
With other ototoxic drugs
Known hypersensitivity
Pregnancy
Route of administration
Intravenous 1g
Side effects
Irregular heartbeat
Loss of appetite
Difficult,burning urination
Nausea
Decreased urine
Seizures
Bloody or cloudy urine
Unusual weight gain or loss
Bladder pain
Mechanism of action
Resulting in inhibition of the transpeptidase
Prevents further elongation
During cell wall synthesis
And cross -linking of the peptidoglycan matrix
By binding to the D -ALa-D -ALa terminals of growong peptide chain
Inhibit cell wall synthesis
Indication
Staphylococcal endocarditis
Infection of the lower respiratory tract
Storage
Store between 2 -8 °C
14 days at room temperature refrigeration