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diltiazem download (5) (mechanism of action (it also decrease heart rate…
diltiazem
trade name
cardizem
indications
used to treat hypertention
angina
and certain heart arrhythmias
side effects
asthenia
headache
edema
dizziness
fever
hoarseness
route to administer
oral
intravenous
storage
refrigerate liquid injection vials,protrct from freezing
may store at room temperature for 1 month
contraindications
bradycardia
impaired left ventricle functuion
atrioventricular node conduction disturbances
peripheral artery occlusive disease
contraindicated in the presence of sick sinus syndrome
chronic obstructive pulmonary disease
mechanism of action
it also decrease heart rate and reduce the degree
of systolic anterior motion
relaxation in hypertrophic cardiomyopathy
diltiazem improves early diastolic left ventricular
it does this by binding to L-type calcium channels
in the heart and reducing systolic calcium
entry into myocardial and automatic cells