Amlodipine 
Trade names
Norvasc
Keterzia
Indications
Treat high blood pressure
Help prevent stroke, heart attack and kidney problems
Treat chronic stable angina,
Vasospastic angina
Side effects
Dizziness
Lightheadedness
Swelling ankles/ feet
Flushing
Contraindications
Liver or kidney problems
Heart attack
Severe hypotension
Haemodynamically unstable
Shock
Hypersensitivity to dihydropyridine
With obstruction of left ventricle
Storage
Keep in original container, tightly closed
Store at a room temperature
Keep away fron heat, mm and moisture
Store suspension in the fridge, avoid freezing
Keep out of reach of children
Mechanism of action
Is a dihydropyridine calcium antagonist
Inhibits transmembrane influx of calcium ions
Into vascular smooth muscle and cardiac muscle
Binds to dihydropyridine and nondihydropyridine binding sites
Depending upon movements of intracellular calcium ions
Amlodipine is peripheral arterial vasodilator
That acts directly on vascular smooth muscle
To cause reduction in peripheral resistance
And reduction in blood pressure
Route of administration
Oral