Please enable JavaScript.
Coggle requires JavaScript to display documents.
PROPOFOL (Side effect (Burning/Stinging IV site, Apnea, Muscle pain,…
PROPOFOL
Side effect
Burning/Stinging IV site
Apnea
Muscle pain
Pruritis
Arrhythmias
Pain at injectiin site
Bradycardia
Mechanism of action
Decreases the rate of dissociation of the GABA
From receptor ,thereby increasesthe duration activated GABA
Increases GABA mediated inhibitory in the CNS
Opening chloride channel resulting hyperpolarization of the cell membrane
Related to its interaction with gamma aminobutyric acid
Contra indication
Obsterical procedures
Anaesthesis in children below 3 years
Hypesensitivity to propofol
Airway obstruction
Indication
Sedation in intensive care unit
Treatment of refractory nauseain patient receiving chemotherapy
Induction and maintenance ofgeneral anasthesia
Treatment of status epileptics
Storage
Do not store below 25°c
Used within 6 hours once opened
Route of administration
Intravenous 10mg/ml