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AMIODARONE (Side effect (Blurred vision, Involuntary body movements,…
AMIODARONE
Side effect
Blurred vision
Involuntary body movements
Constipation
Dyspnea
Bradycardia
Paresthesia
Pneumonitis
Temor
Persistent ventricular tachycardia
Mechanism of action
Prolonged effective redractory period in cardiac myocytes
Myocyte excitability is decreased
Results in increased action potential duration
Preventing rerentry mechanism
Block potassium rectfier responsible for repolarization
Ectopic foci from perpectuating tachyarrhymias
Contra indication
Second or third degree AV block
Symptomatic bradycardia
Severe sinus node dysfunction
Know hypesensitivity
Cardionergic shock
Indication
Ventricualr fibrillation
Supracentricular tachycardia
Ventricular tachycardia
Storage
Do not refregerate
Keep ampoules in the outer carton to protect from light
Do not store above 25°C
Route of administration
Intravenous and orally