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Diltiazem Screenshot_20200419-194108 (Mechanism of action (Non…
Diltiazem
Brand names
Cardizem
Dilacorxr
Indications
Treat high blood pressure
Treat chest pains
Side effects
Headache
Dizziness
Bradicardia
Fluid build up
Nausea and vomiting
Rash
Liver problems
Weakness
Mechanism of action
Non dihydropyridine calcium channel blocker
Inhibits intracellular calcium ion reflex
Across membranes of myocardial cells
And vascular smooth muscle contraction
Thereby dilating main coronary and system arteries
No effect on serum calcium concentrations
Substantial inhibitory effect on cardiac conduction system
Acting principally at AV nodes
With some effects on sinus node
Route of administration
Intravenous
Intravenous
Storage
Refrigerate liquid injection vials
Protect from freezing
Powder-keep at roo temperature
Solutions stable at room temperature for 24 hours
Contraindications
Hypotension
Gastro esophageal reflux disease
Sick sinus syndrome
Ventricular syndrome
Hepatic disease
AV block
