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PARASYMPATHOMIMETIC DRUGS (BETHANECHOL (Contraindications (Peptic ulcers,…
PARASYMPATHOMIMETIC DRUGS
BETHANECHOL
Contraindications
Peptic ulcers
Mechanical obstruction
Asthma
Seizures
Hypersensitivity to the drug
Hyperthyroidism
Side effects
Diarrhoea
Salivation
Vomiting
Anorexia
Indications
Acute, non-obstructive, postoperative or postpartum urinary retention
Storage
Store at room temperature between 15-30 degrees C
Away from light and moisture
Mechanism of action
Stimulates parasympathetic receptors
Increase bladder muscle tone
Causes contraction and stimulates micturtion
Stimulates cholinergic receptors
Route of administration
Oral tablet
Parenteral solution available
CARBACHOL
Mechanism of action
Stimulates cholinergic receptors in the eye
Causes miosis and increases aqueous humor outflow
Acts on muscarinic and nicotinic receptors
Produces constriction of the iris and ciliary body
Reduces intraocular pressure
Induces rapid eye movement sleep
Activates postsynaptic muscarinis acetylcholine receptors
Indications
Glaucoma
Opthalmic surgery
Contraindications
Gastroduodenal ulcers
Asthma
Coronary disease
Side effects
Vision prblems
Irregular breathing
Drowsiness
Eye irritation
Corneal clouding
Stinging of the eye
Headache
Storage conditions
Store at room temperature between 8-27 degrees C
Route of administration
Topical ocular or intraocular injection