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Renal Physiology II (Glomerular filtration (layers (OUT, epithelium ( have…

- - - - .
      - 10-18 renal pyramids -- a part of nephron is here
        
        transport urine from the cortical, or outer, part of the kidney, where urine is produced, to the calyces
        
        renal papilla -- at the tips of the renal pyramid
        
        transport urine from kidney cortical section
        
        major calyces -- a big branch to the renal pelvis
        
        transport urine in or out
        
        minor calyces -- smaller branches of major calyx
        
        passes through a renal papilla at the apex
      - .
        
        NEPHRON
        
        Renal corpuscle
        
        glomerulus
        
        have bowman capsule (renal cells that surrounds it)
        
        blood flow -- sodium can pass through the endothelial lining -> basement membrane -> epithelium -> other part of nephron
        
        epithelium made by podocyte ( wrap around the basement membrane)
        
        have filtration slits to allow passage water, glucose and ionic salt BUT NOT large protein and RBC
        
        layers:
        OUT
        epithelium ( have filration slits between -- like octopus)
        basement membrane
        endothelium
        IN
        
        Renal Tubule
        
        Proximal convoluted tubule
        
        bulk absorption of filtered water and solutes
        
        loop of henle
        
        2 more items...
- - - - angiotensin 2 directly increase systemic bp and renal perfusion pressure, activates sodium uptake in proximal tubule and collecting tubule and stimulates release of aldosterone from adrenal gland and vasopressin from the pituitary.
- - - - treatment
        
        cat probably benefit initially from rehydration with intravenous fluids and correction of electrolyte and acid base disturbance as dictated by the serum chemistry profile. should include diet containing low protein that is high in bioavailability, low sodium and low phosphorus
      - serum creatinine level is elavated bcs progressive loss of glomerular function has severely reduced the GFR and the creatine isnt cleared from the plasma normally, urine isnt concentrated in response to dehydration bcs tubular function is also comprimised