Anistreplase Screenshot_2020-04-18-10-40-12-1

Contraindications

Storage

Dosage

Indications

Side Effects

Mechanism of action

Route of Administration

Myocardial infarction

Pulmonary embolism

Thromboembolic disorders

Haemorrhage and recent stroke

Cerebral neoplasm

Severe hypertension

Pregnancy

Increased risk of cerebral bleeding

IV 30 u over 5 mins as a single dose img immediately after onset of symptoms

Anistreplase consist of a complex of the lys-form of plasiminogen and streptokinase with the addition of a p-anisoyl

Group that undergoes deacylation upon IV injection to release the active complex which converts plasminogen to plasmin which has fibrinolytic activity

Bleeding

Irregular heart rhythms

Intravenous (IV)

store at room temperature of 20°c to 25°c