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Alteplase Screenshot_2020-04-19-13-20-57-1 (Contraindications (Increased…
Alteplase 
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Dosage
0.9 mg/kg (with 10% of the total dose administered as an initial IV bolus over 1 mins and infuse 60 mins
Side Effects
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Allergic reaction (swelling,rash,hives )
Mechanism of action
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When in the systemic circulation ,alteplase binds to fibrin in a thrombus and initiates fibrinolysis
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