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Clioquinol 1% with flumethozone Screenshot_20200418-180927 (Mechanism of…
Clioquinol 1% with flumethozone
Brand names
Locarten
Vioform
Indications
Treat external ear infections
Treat middle ear infections if combined with oral antibiotics
Side effects
Stinging
Rash
Redness
Itching
Swelling
Servere ear pain
Headache
Vision problems
Increased thirst and urination
Contraindications
Lesions of the eye
Diaper rash
Children under 2 years
TB of the skin
Mechanism of action
It is a broad-spectrum antibacterial agent
But mechanism of action is unknown
Hydrocortisone is a corticosteroid
That diffuses across cell membranes
Forming complexes with specific receptors
And further binds to DNA
And stimulate transcription of mRNA
And subsequent protein synthesis
Of various enzymes through ultimately responsible
For anti-inflamatory effects of corticosteroids
Applied topically to the skin
Route of administration
Topical
Ear drpos3
Storage
Store between 2-30°C
Keep away from light and moisture
