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Neomycin Screenshot_2020-04-18-17-07-58-1 (Contraindications (The…
Neomycin
Contraindications
The presence of intestinal obstruction
Patient with impaired renal function
Hypersensitivity
Patient receving high dosage are at increased risk of toxicity
Mechanism of action
The 30s ribosomal subunits of susceptible bacteria
Active by transported into the bacterial call where I binds to receptor
It inhibits bacterial protein synthesis through irreversible binding
Side effects
Nuasea or vomiting
Decrease urination ,mild diarrhea
irritation or soreness of the mouth or rectal area
Route
administered via oral
Storage
Stored between 2 to 8 degrees Celcius
Dosage
500 mg twice a day
Indications
It is used to lower the signs of hepatic coma
to treat bacterial infection
It is used to prevent infection during bowel surgery