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alendronic (contraindications (Hypocalcemia, Pregnancy and breastfeeding,…
alendronic
contraindications
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Inability to stand, walk, or sit for 30 minutes after oral administration
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side effects
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osteonecrosis of the jaw,
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mechanism of action
Alendronate inhibits osteoclast-mediated bone-resorption. Like all bisphosphonates, it is chemically related to inorganic pyrophosphate, the endogenous regulator of bone turnover.
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