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Androgens & Anti-Androgens (Male hormonal drugs) ((Side effects (Hot…
Androgens & Anti-Androgens (Male hormonal drugs)
Mechanism of action
Bicalutamide is an anti-androgen that works by preventing the actions of Androgen
Indications
Used in combination therapy with other hormonal drugs to treat Prostate Cancer
Contra-indications
Diabetic patients
Anemia
Hypersensitivty to drug
Abnormal liver function test
Side effects
Hot flushes
Breast swelling/tenderness/pain
Nausea & vomiting
Diarrhoea
Constipation
Weight changes
Headache
Insomnia
Drowsiness
Dizziness
Storage conditions
Room temperature
Protect from light
Moisture
Keep away from children
Route of Administration
Oral administration.
Oxymetholone
Indications
Oxymetholone is used in the treatment of low blood cell count (Anaemia).
Contra-indications
High blood calcium levels .
Diabetes
High cholesterol
Heart disease
Kidney disorder
Enlarged prostate
Mechanism of action
Oxymethelone is a synthetic male hormone which works by increasing the amount of the hormone (erythropoietin) which is involved in the production of red blood cells.
Side effects
nausea, ,&
yellowing of the skin or eyes.
Upper stomach pain
Rapid weight gain localised on face and midsection
Loss of appetite
Dark urine,
Clay-coloured stools
Yellowing of skin or eyes
Storage conditions
Protect from light.
Store at room temperature
Route of administration
Oral
Intramuscular
Subcutaneous.
Contra-indications
Degarelix is contraindicated in Pregnancy
Side effects
Hot flushes
Weight gain
Increased sweating & night sweats
Back or joint pain
Tiredness
Dizziness
Nausea
Headache
Constipation.
Indications
Degarelix is used in the treatment of advanced Prostate Cancer
Storage conditions
Degarelix should be stored in a cool dry place
Mechanism of action
Degarelix is a GnRH receptor antagonist.
Binds reversibly to the pituitary GnRH receptors
Reducing the release of gonadotropins and consequently testosterone
Reducing the growth of Prostate Cancer
Route of administration
Subcutaneous injection
Bicalutamide
Degrarelix