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Somatrophin (Indications (GH deficiency in adults, Replacement of Growth…
Somatrophin
Indications
GH deficiency in adults
Replacement of Growth hormone
Aids wasting and cachexia
Long term treatment of children with growth failure
Growth of internal organ
Protein synthesis
Contraindications
Cranial lesions
Abdominal surgery
Allergic to the drug
Pregnancy or lactation
Side effects
Swelling
Joint pain
Development of antibodies
Endocrine reactions(hypothyroidism, insulin resistance)
Mechanism of action
Binds to dimeric growth hormone receptors
Results in intracellular signal transduction
Route of administration
Intramascular route
Subcautneously
Storage of conditions
Reconstitute the drug
Classification
Growth hormone agonists