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methysergide download (3) (side effects (diarrhea, drowsiness, abdominal…
methysergide
indications
used to episodic and chronic migraine
for episodic and chronic cluster of headaches
mechanism of action
leading to vasoconstriction
also responsible for alpha-adrenergic blocking activity
which directly stimulates smooth muscle
is serotonin antagonists acts on central nervous system,
route to administer
oral
also available for IM & IV
dosage
adults 4-8mg daily
side effects
diarrhea
drowsiness
abdominal pain
heartburn
nausea and vomiting
insomnia
contraindications
lactation
peripheral vascular disease
pregnancy
severe hypertension
hypersensitivity to methysergide or to tartrazine
cellulitis of the lower limbs
storage
at room temperature
away from sunlight and moisture
