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Phenylbutazone Screenshot_20200418-182717 (Side effects (Ulceration,…
Phenylbutazone
Mechanisms of action
Binds and activates prostaglandin H synthase and prostacylin synthase through peroxide mediated
Deactivation leads to reduced inflammation of surrounding tissue
Side effects
Ulceration
Abdominal burning
Cramping
Gastritis liver toxicity
Route of administration
Orally
Intravenously
Dosage
4.4mg once or twice a day
Storage
Store at room temperature below 30°c
Out of reach of children
Contraindications
In patients with ulcers
Asthmatic patientd
Patients with. GIT infections
Nursing considerations
Tell patient to follow prescribed diet and medication
Exercise regimen to prevent hypoglycemic episodes
Concurrent use of alcohol
Indications
Indicated for patients with unknown infections
