obesity drugs

ORLISTAT

mechanism of action

works by inhibiting gastric and pancreatic lipases

the enzymes that breaks down triglycerides in the intestines.

when lipase activity is blocked,triglycerides from the diet are not hydrolised into absorbable free fatty acids and instead excreated unchanged.

indications

it is indicated for obesity management including weight loss and weight maintanance when used in conjunction with a reduced calorie diet.

contraindications

hypersensitivity to orlistat

reduced gallbladder function

pregnancy and breastfeeding

anorexia and bulimia

side effects

flatulance

fatty or oily stools

oily spotting on underwear

increased number of bowel movements

abdominal pain or discomfort

storage conditions

store in the temperature of 2-8 degrees celcious

route of administration

taken oraly

SIBUTRAMINE

route of administration

taken orally

storage conditions

capsules are stored at 25 degrees celcious

mechanism of action

it exerts its pharmalogical actions predominantly via its secondary M1 and primary M2 amine metabolities.

by inhibiting the reuptake of these neurotransmitters,

it promotes a sense of satiety and decrease in appetite thereby reducing food intake.

indications

for the treatment of obesity and maintanance of weight loss.

contraindications

contraindicated in patient with pscychiatric conditions as bulimia nervosa and serious depression

patients with history of a predisposition of drug or alcohol abuse

hypersensitivity to the drug or any of the inactive ingredience.

side effects

flu symptoms

sore throat

cough

runny or stuffy nose

high blood pressure

fast or pounding heart beat

seizures

it is contraindicated in malabsprption