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SUMATRIPTAN IMG_20200419_122831 (Contraindications (Arteriosclerosis,…
SUMATRIPTAN
Indications
Imitrax injection for adults with acute migraine, with or without aura
Acute treatment of cluster headache
Mechanism of action
Thereby constricting cerebral blood vessels
This may lead to a relief in pain from vascular headaches
Sumatriptan selectively binds to and activate serotonin 5-HT1D receptors
A sulfonamide triptan with sumatriptan makes vasoconstrictor activity
Contraindications
Arteriosclerosis
Silent myocardial ischemia
Vasospactic angina such as prinzmetal's variant angina
Acute myocardial infarction
Angina pectoris
Patients with known coronary artery disease
Side effects
Weakness
Drowsiness
Feeling of tingling /numbness /pricking and heat
Dizziness
Flushing
Storage condition
Room temperature of 25-30 degrees Celsius
Route of administration
Subcutaneous
Intranasal
Oral
Rectal