Corticosteroids drugs
Prednisolone
nursing consideration
indication
Mechanism of action
side effects
Storage condition
Contraindication
Route of administration
Stores at 20-25 degrees
Oral
weight gain
Seizures
Bloating
Menstrual period changes
Acne
Acute viral infection
Peptic ulcer disease
Hypersensitivity
Hepatic dysfuction
Pregnancy
Allergic conjunctivitis, keratitis, allergic corneal
Chronic obstructive pulmonary disease
Hematologic disorders
Endocrine disorders
Neoplastic disease
Protect from light and moisture
Slow wound healing
increased appetite
5-10 mg 4 times a daily
Connective tissue infections
Tuberculosis meningitis
Prednisolone in liver.
Mild mineralocorticoid activity t & moderate ant inflammation effects
Commonly used glucocorticoid due to high activity
Controls or prevents inflammation by controlling rate of protein synthesis
Suppresses migration of fibroblasts
Reverses capillary permeability & stabilizes lysosomes at cellular level
Betamethasone
indication
Nursing consideration
Mechanism of action
side effects
Storage condition
Contraindication
Route of administration
Receives capillary permeability & lysosomal stabilization at the cellular level to prevent inflammation.
Clotrimazole is anti-fungal agent that bind to phospholipid in fungal
Leads to control the rate of protein synthesis, depresses migration of leukocytes.
Cell membrane altering cell wall permeability resulting in loss of essential intracellular
It is a glucocorticoid receptor agoinst.
Eczema
Psoriasis
Dryness
Crusting
Reduces swelling
0.6 mg / 5 mL
Stored below 25 degrees celcious
Insomia and headache
Behavioural changes
Muscle weakness
Seizures
Abdominal pain
Hypersensitivity to the drug
Traumatic brain injury
Systemic fungal infection
Untreated serious infection
Do not administer to patients with active Tuberculosis
Blurred vision
Reduces itching
Dermatitis
Protect from light & freezing
It becomes actives when it is not bound to transcortin
Dexamathesone
Indication
Nursing consideration
Mechanism of action
Side effects
Corticosteriods increase the production of HMF CoA
Allows cell to make more of their own cholesterol ,increases circulation of low density lipoprotein
Increases gluconeogenesis & increases blood glucose level
Chronic use results in serum cholesterol, deposition of fat results in Cushing syndrome.
Binding to cellular DNA results in changes in metabolic of carbohydrates.
Arthritis
Breathing problems
Spinal cord injury
Eye condition
Asthma
Blood /hormone /immune system disorders
Storage conditions
Contraindication
Route of administration
Osteoroposis
Euphoria
stored at room temperature, away from light
Oral take with food or milk to prevent stomach upset
Increased appetite
Restlessness
Weight gain
Headache
Menstrual changes
Psychoses
Diabetes
Sepsis
Hypertension
Peptic ulcer
Infectious disease
take daily before 9 am
Decreased in protein production