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Renal/ Urological System Pathologies (Genetic mutation at 16p13 &…
Renal/ Urological System Pathologies
Genetic mutation at 16p13 & 4q21-22
Polycystic Renal Disease: Multiple cysts in kidneys & dysfunction
back pain, fever, costovertebral angle tenderness, hematuria
Hypercalcemia, bone disease, hyperparathyroidism, accumulation of calcium oxalate
Nephrolithiasis
Severe back pain with radiation to the groin, abdominal pain, chills & fever, dysuria, frequency
Hydroureter
Hydronephrosis
Ureterohydronephrosis
GABHS, staphylococci bacteria, viruses, ischemia, drugs toxins, DM, lupus
Antibodies attack glomerular membranes
antigen-antibody complexes develop & deposit in glomerular membranes, causing inflammation
Glomerulonephritis
Back pain, periorbital edema, fever, cola-colored urine, malaise
Nephrotic syndrome
Periorbital edema, proteinuria, weight gain, fatigue, loss of appetite
Childbirth, aging, weak pelvic muscles
Relaxed pelvic floor muscles with increase abdominal pressure
Stress Incontinence
Neurogenic (CVA, Parkinson's, MS), mylogenic (aging,DM)
Urge Incontinence
Benign prostatic hyperplasia
Overflow incontinence
UTI ascends into upper urinary tract
Infection & inflammation of upper urinary tract
Pyelonephritis
Fever, malaise, chills, back pain, dysuria, frequency, urgency,
pyuria