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Methotrexate Screenshot_20200412-101653-1 (Adverse effects (Hypotension,…
Methotrexate 
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Mechanism of action
Decrease swelling, pain and stiffness in rheumatoid arthritis.
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Nursing implications.
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Tell the patient about dosing regimen , as accidentally dose-
Throughout the therapy and immediately report vomiting,
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Patients should be advised to report fever, cough, chest pain.
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Exposure, as hypersensitivity reaction may occur.
Contraindications
Liver/renal disorders, immunodeficiency syndrome,
Blood discrasias, peptic ulcer disease, ulcer active colitis,
Contraindicated in patients with poor nutrition ,
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Dose and route
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It can be given : PO, IV , IMI, Subcut.
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