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BIOL221 Exam 3 (Innate Immunity (Physical Barriers (Mucus membranes…

- - - - ciliated epithelial cells
        
        Cilia
        
        Move to sweep trapped bac out of mucus membranes
        
        remove them from body
      - Mucus
        
        Sticky
        
        Traps Bac
      - Portals of entry
        
        Digestive tract
        
        Resiritary Tract
        
        Urogenital Tract
    - - prevents overgrowth by pathogen
      - Good bac that prevent bad bac from taking over
    - - Removal of inhaled particles
    - - Antimicrobial factors
        
        Lysozyme
        
        Peroxidase
        
        lactoferrin
        
        binds to Fe
        
        Bacteria and body fight over supply of Fe
  - - - Granulocytes
        
        produce cytokines
        
        proteins that signal
        
        chemokines
        
        mediate chemotaxis to infection site
        
        interferon
        
        interfere with viral replication
        
        Alpha&Beta
        
        1 more item...
        
        interleukins
        
        communicate b/w WBC
        
        growth & differentiation
        
        Inflammation
        
        1 more item...
        
        tumor necrosis factors
        
        kill tumor cells
        
        kill infected cells
        
        inflammatory
        
        granules with stuff in them
      - Monocytes
      - Lymphocytes
        
        B cells
        
        antibodies
        
        T cells
        
        Tc
        
        Th
        
        NK cells
        
        kill virus infected cells
        
        kill tumor cells
  - - - TLR
        
        phagocyte membrane
      - RLR,NLR
        
        in cytoplasm
    - - pathogen associated molecular patterns