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Bezafibrate bezafibra (Mechanism of Action (Reduction of hepatic…
Bezafibrate
Route of Administration
Oral route
Side effects
Itchy skin
Dizziness
Nausea
Headache
Upset stomach
Contraindications
Gallbladder disease
Hypersensitivity to bezafibrate
Renal impairment
Pregnancy or lactation
Hepatic impairment
Mechanism of Action
Reduction of hepatic triglyceride production
Induction of hepatic fatty acid (FA) uptake
Induction of lipoprotein lipolysis
Induction of β-oxidation decrease in FA synthesis by fibrates
Increased removal of LDL particles
Reduction in neutral lipid
Increase in HDL production and stimulation of reverse cholesterol transport
Indications
Hyperlipidaemia
Hypercholesterolemia
High triglyceride levels
Storage conditions
Store medication away light
Store medication in a dry place
Store medication away from heat
Keep medication in a lock
Store medication at 15 to 30 degrees C
