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Azathioprine Azathioprine (Side effects (Rash, Fever, Diarrhea, Tiredness…
Azathioprine
Indications
Prevention of rejection in renal homotrabsplantation
Active rheumatoid arthritis
Mechanism of action
Inhibits lymphocyte activitiin by inhibiting the calcineurib pathway
Inhibits the purine pathway and diminish cell proliferation
Nursing considerations
Monitor signs of hypersensitivity reactions such as muscle pain
Side effects
Rash
Fever
Diarrhea
Tiredness
Muscle aches
Liver damage
Dizziness
Hypotension
Route of administration
Administered intravenously
Storage conditions
Store at room temperature between 15-25 degrees
Contraindications
Severe decrees in white blood cells
Blood clot in a liver vein
Decreased blood playelets
Scute inflammation of pancreas
Significant anemia
Pregnancy
Bad infection
Malignant lymphoma