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Endorphins image-20160331-28445-kns6qy (Mechanism of action (Inhibiting…
Endorphins
Mechanism of action
Inhibiting pain signals in peripheral nerves
By blocking the neurotransmitter substance P
They bind at u-,receptors
They act on both nervous and peripheral nervous system
Indications
Addictive disorders
For pain
Severe depression
Psychosis
Contraindications
Known hypersensitivity to the drug
Addicticted patients
Nursing considerations
Assessment for urinary retention and inform the doctors
Side effects
Constipation
Physical and psychic dependancy
Respiratory deppression
Storage conditions
Store at room temperature of 15-25 degrees
Route of administration
Orally
