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CUSHING SYNDROME Screenshot_20200413_010143 (CLINICAL MANIFESTATIONS (• …
CUSHING SYNDROME
DEFINITION
• A condition that occurs from exposure
• To high cortisol levels
• For a long time
PATHOPHYSIOLOGY
• When a body is exposed to
• High levels of cortisol
• For a long time
• Too much cortisol produces
• The hallmark signs of cushing
CAUSES
• Excess cortisol
• Pituitary adenoma
• An ectopic ACTH secreting tumour
• Primary adrenal gland disorder
• Familial cushing syndrome
CLINICAL MANIFESTATIONS
• Weight gain
• Fatty tissue deposits
• Moon face
• Buffalo hump
• Hirsuitism for women
• Irregular menstrual periods
• Decreased libido
• Decreased fertility for men
• Erectile dysfunction
• Fatigue
• Muscle weakness
• Depression, anxiety and irritability
• Loss of emotional control
• Cognitive difficulties
NURSING CARE PLAN
• encourage rest and activity
• preparing patient for surgery
• promoting skin integrity
• decrease risk of injury
• decrease risk of infection
• improving body image
• monitoring and management of complications
HEALTH EDUCATION
• advice patient about the condition
• health educate healthy eating
• encourage adequate intake of water
• encourage daily exercise and activities
• encourage follows ups
PHARMACOLOGY
• ketoconazone
• lysoden
• metopirone
• korlym
• mefeprex
TREATMENT
• Reducing corticosteroid use
\
• surgery
COMPLICATIONS
• Osteoporosis
• Hypertension
• Diabetes
• Infections
• Loss of muscle mass and strength
DIAGNOSTIC TESTS
• Urinalysis
• Blood tests
• Saliva tests
• Imaging tests
