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Methotraxate (Contraindications (Thrombocytophenia, Alcoholic hepatic…
Methotraxate
Contraindications
Thrombocytophenia
Alcoholic hepatic disease
Decreased function of bone marrow
Pleural effusion
Anaemia
Psoriasis
Side effects
Pulmonary fibrosis
Lymphoma
GI upset
Lung disease
Liver cirrhosis
Mechanism of action
It inhibits enzymes involved in purine metabolism
This leads to accumulation of adenosine
Indications
Treatment of chronic athritis
Route of administration
Administered orally
Storage
Stored at room temperature