Please enable JavaScript.
Coggle requires JavaScript to display documents.
PROTEASE INHIBITORS (Fosamprenavir (Side effects (Abdominal pain, Headache…
PROTEASE INHIBITORS
Fosamprenavir
Side effects
Abdominal pain
Headache, rash
diarrhoea
Increased serum lipase
Nausea, vomiting
Contraindications
Co-administration with ritonavir
Hypersensitivity to the drug
Route if adminstration
Oral
Indication
HIV infenction
Storage condition
Store in room temperature (20-25 degrees C)
Mechanism of action
Hydrolysed to amprenavir
Inhibits HIV-1 protease
Interferes with the HIV replication process by binding to the active site of HIV-1 protease
Forms immature non-infectious viral particles
Ritonavir
Side effects
Hepatotoxicity
Taste changes
Pancreatitis
Abdominal pain
Hyperglycemia
Vasodilation
Atrioventricular blockage
Rash
Exfoliative dermatitis
Thrombocytopenia
Route of administration
Oral
Contraindications
Hypersensitivity
Hepatic impairment
Ischemic disease
Heart disease
Cardiomyopathy
Hemophilia
Storage condition
Stored in room temperature (20-225 degrees C)
Indication
HIV-1 infection
Mechanism of action
Inhibits HIV viral proteinase enzyme
Prevents cleavage of the polyprotein
Release of non-infectious immature viral particles