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Phenytoin (Side effects (Megaloblastic anemia, Nystagmus, diplopia, ataxia…
Phenytoin
Side effects
Megaloblastic anemia
Nystagmus, diplopia, ataxia
Megaloblastic anemia
Osteopathies
Peripheral neuropathy
Teratogenic: fetal hydantoin syndrome
Hirsutism
Contraindications
Patients with diabetes
allergies
Known hypersensitivity
Porphyria
osteomalacia
Low blood pressure
An autoimmune disease
Storage
Protect from light
Do not freeze
Store at 20 to 25 degrees celcius
Mechanism of action
Inactivation of Na+ channels
Zero-order elimination
Indications
First-line treatment for tonic-clonic seizures and for status epilepticus prophylaxis
prevention and treatment of seizures occurring during neurosurgery
Route of administration
Inject slowly intravenously at a rate of 3mg/min