Pituitary drugs
Corticotropin
Mechanism of action
Acts through stimulation of cell surface ACTH receptors which are primarily located on the adrenocortical cells , stimulation of the cortex of the adrenal gland by corticotropin and then boosts the synthesis of corticosteriods
Indication
Treatment of infantile spasms ,multiple sclerosis and asthma
Contraindications
Hypercortisolism
Chronic heart failure
Adrenal insufficiency
High blood pressure
Inflammation of the esophagus
Side effects
Acne
Fluid retention
Constipation
Nausea
Heartburn
Storage condition
Route of administration
Store in the refrigerator ,do not freeze
Intravenously
Subcutaneous
Intramuscular
Metotropin
Mechanism of action
Metropins contain follicle-stimulating hormone and Luteinizing hormone ,Metropins prepare the ovarian and testicular function, the combination of FSH and LH stimulates follicular growth and maturation.
Indication
used for multiple follicular development and ovulation induction in patients who have previously received pituitary suppression
Contraindications
Uncontrolled thyroid and adrenal dysfunction
Ovarian cysts
A high FSH level
Abnormal bleeding of undetermined origin
Side effects
Vaginal bleeding
Fever
Headache
Pain at the injection site
Breast tenderness
Storage condition
Store in the refrigerator or at room temperature between(3-25 degrees C)
Route of administration
Intramuscular
Subcutaneous